Uterine carcinoma ndi chikhalidwe chomwe chimayamba pamene maselo a chiberekero akuchulukana mopanda mphamvu m'chiwalo chamkati cha mkazi. Khansara yamtunduwu nthawi zambiri imakhudza njira zoberekera za akazi. Chiberekero ndi chiwalo chooneka ngati peyala, chomwe chili m’chiuno cha mkazi pakati pa mafupa a m’chiuno mwake. Maselo athanzi akayamba kukula ndi kusintha, kukula kosalamulirika ndi kuberekana kumayambitsa khansa ya m’chiberekero kupanga chotupa, chomwe chimatchedwa chotupa. Azimayi ambiri omwe ali ndi matendawa akhala akusiya kusamba. Nthawi zina imatchedwa khansa ya uterine ndipo ndi khansa yofala kwambiri padziko lonse lapansi. Ndi chithandizo choyenera cha khansa ya chiberekero ndi chithandizo cha matenda, khansara iyi imachiritsidwa. Kuchotsa chiberekero ndi chithandizo choyamba chomwe chimaperekedwa kwa odwala omwe akhudzidwa. Poyerekeza ndi mitundu ina ya khansa, imakhala ndi moyo wapamwamba kwambiri.

Uterine carcinoma ndi matenda omwe amapezeka pamene pali kukula kosalamulirika kwa maselo a chiberekero mwa mkazi. Kawirikawiri, mtundu uwu wa khansa umagwirizanitsidwa ndi ziwalo zoberekera za akazi. Chiberekero ndi kachiwalo kakang'ono kamene kamakhala m'chiuno mwa mkazi pakati pa mafupa awiri a m'chiuno. Kawirikawiri kukula ndi kusintha maselo athanzi, kulephera kulamulira kukula kwakukulu ndi kubereka komwe kumabweretsa khansa ya uterine kumapangitsa kuti pakhale misala yotchedwa chotupa.

Mitundu ya Khansa ya Uterine

Pali mitundu iwiri ikuluikulu ya matenda a chiberekero cha amayi:

Khansa ya Endometrial: Ndi mtundu wa khansa womwe umachokera ku khansa ya endometrial yomwe imayambira ku chiberekero cha chiberekero, ndipo nthawi zambiri imagwirizanitsidwa ndi kuchuluka kwa estrogen m'thupi. Poyerekeza ndi mtundu woyamba wa khansa ya endometrial yomwe imakula pang'onopang'ono, khansa yamtundu wa 2 endometrial imakula mofulumira kwambiri ndipo imakhala ndi chizolowezi chofala kwambiri.
Uterine sarcoma: Uwu ndi mtundu umodzi wa zotupa zomwe sizimadziwika kuti khansa ya m'chiberekero. Amachokera ku minofu ya chiberekero kapena minofu ina yolumikizana ya chiberekero m'malo mwa endometrium. Nthawi zambiri, ma sarcoma a uterine amakhala ankhanza komanso olimba kuchiza kuposa khansa ya endometrial.

Mitundu Ina ya Khansa ya Endometrial

Serous adenocarcinoma: Zotupazi zimakhala ndi chizolowezi chofalikira ku ma lymph nodes ndi mbali zina za thupi.
Adenosquamous Carcinoma: Mtundu wachilendo uwu wa khansa ya chiberekero imagwirizanitsidwa ndi squamous cell carcinoma ndi endometrial adenocarcinoma ya kunja kwa uterine wosanjikiza.
Uterine Carcinosarcoma: Ichi ndi chochitika chapadera cha chiberekero cha carcinosarcoma. Lili ndi maselo a khansa omwe amafanana ndi sarcoma ndi khansa ya endometrial. Pali mwayi waukulu woti khansa yamtunduwu imatha kufalikira ku ma lymph nodes ndi ziwalo zina.
Papillary Serous Carcinoma: Ndi milandu yochepa chabe yomwe yadziwika padziko lonse lapansi chifukwa chosowa kwambiri.

Zomwe Zimayambitsa Khansara ya Uterine & Zowopsa

Zinthu zina zomwe zingapangitse chiopsezo cha khansa ya uterine ndi izi:

Kunenepa kwambiri kapena kunenepa kwambiri
Mbiri yachipatala kapena mbiri ya banja la khansa ya uterine, ovarian, kapena matumbo
Kutaya magazi kwambiri kapena kwanthawi yayitali
Kusadziletsa
Kusiya kusamba mochedwa
Kuthamanga kwa magazi
shuga
Nthawi yoyambira asanakwanitse zaka 12
Matenda a Polycystic ovary (PCOS)
Age
Zakudya zamtengo wapatali

Zizindikiro za Khansa ya Endometrial & Zizindikiro Zochenjeza

Zizindikiro zosiyanasiyana za khansa ya endometrial kapena uterine sarcoma zalembedwa pansipa:

Kupweteka kapena kupweteka m'chiuno
ululu m'mimba
Kufooka
Kupweteka pokodza
Kutuluka magazi kwambiri pausinkhu wa zaka 40 kapena kupitirira
Kutuluka koyera kumaliseche
Ululu pa nthawi yogonana
Kutaya magazi m'nyini musanayambe kusintha
Magazi mu pee
Mawanga ochepa kapena kutuluka magazi pambuyo posiya kusamba

Gawo la Khansa ya Uterine

Gawo la khansa ya endometrial ndilofunika kwambiri kuti munthu adziwe zomwe akuyembekezera kuti athandizidwe ndi chithandizo. Zotupa pamagawo ofanana zimakhala ndi momwe zimachitikira ndipo nthawi zambiri zimathandizidwa mofanana.

Gawo 1: Amatanthauza khansa yomwe imapezeka m'chiberekero.
Gawo 2: Gawoli likuwonetsa kuti chiberekero ndi khomo lachiberekero zakhudzidwa ndi chotupacho.
Gawo 3: Gawo lachitatu likuwonetsa kuti khansa yafalikira ku chiberekero, machubu a fallopian kunyini, kapena ma lymph nodes m'mimba kapena chiuno kuchokera pachibelekero/chibelekero.
Gawo 4: Zimatanthawuza kuti khansa imakhudza m'mimba, rectum, chikhodzodzo, ndi matumbo, pakati pa mbali zina za thupi.

Kodi angadziwe bwanji?

Akatswiri azaumoyo angapangire zoyezetsa zina. Izi zalembedwa pansipa:

Kufufuza m'chiuno
Pelvic ultrasound
Endometrial biopsy
Hysteroscopy ndi biopsy
CT & MRI scan
PET kuyesa
Kuyezetsa magazi

Zosankha Zochizira Khansa ya Uterine

Kuphatikiza pa kulingalira za msinkhu ndi matenda omwe ali nawo, dokotala amasankha njira yoyenera ya chithandizo kutengera momwe alili, mawonekedwe ake, ndi mawonekedwe ake. Nazi njira zina zothandizira khansa ya uterine:

Opaleshoni: Ndiwothandiza kwambiri pa khansa ya m'mawere. Pamodzi ndi thumba losunga mazira ndi mazira, chiberekero chimachotsedwa panthawi ya chithandizo cha opaleshoni. Khansara ikafalikira, akatswiri azachipatala amatha kuyang'ana minofu ndi ziwalo zina. Endometrial cancer hysterectomy ndi njira ya opaleshoni yomwe chiberekero ndi khomo lachiberekero zimachotsedwa. Mndandanda wotsatirawu wa mitundu ya hysterectomy imaperekedwa:
- Total m'mimba hysterectomy
- Chithandizo cha nyini hysterectomy
- Kusakanikirana koopsa
- hysterectomy yocheperako pang'ono
Chithandizo cha radiation: Pochita izi, chithandizochi chimatanthawuza kugwiritsa ntchito ma X-ray kapena kuwala kwa radiation kupha maselo omwe ali ndi khansa. Ma radiation a khansa ya endometrial amachepetsa mwayi woti khansayo ibwerere.
Chemotherapy: Pambuyo pa radiotherapy kapena opaleshoni, khansa ikabwerera. Poyamba ankagwiritsidwa ntchito pochiza khansa. Mankhwala amagwiritsidwa ntchito kapena kubayidwa m'mitsempha ya odwala.
Chithandizo cha Mahomoni: Mankhwalawa amaperekedwa pamene khansa yafalikira kapena kubwereranso. Pamene opaleshoni sizingatheke, ndiye dokotala akhoza amalangiza njirayi.
Thandizo Loyang'aniridwa: Ndi mankhwala omwe amalimbana ndi ma cell a khansa kuti khansa isafalikire. Izi zimadziwikanso kuti lenvatinib, pamene khansa imafalikira ndikubwerera.